CJC-1295 no DAC Research Review: Modified GRF 1-29 for GHRH Studies

What CJC-1295 no DAC Actually Is

CJC-1295 no DAC is the “without drug affinity complex” form of the GHRH analog, also known as Modified GRF 1-29 — a 30-amino-acid peptide with a molecular weight around 3368 Da. The “no DAC” distinction matters because the DAC-modified version has a dramatically different pharmacokinetic profile in research settings.

The short version for labs: without DAC, the peptide has a much shorter presence in assays; with DAC, it binds serum albumin and lingers. Your protocol dictates which form you need, so never order them interchangeably.

Why the DAC Distinction Matters

Order CJC-1295 no DAC only if your experimental design requires the unmodified GHRH analog with the shorter research-relevant profile. If your supplier can’t tell you which form they’re selling, that’s a sourcing red flag.

  • CJC-1295 no DAC: ~3368 Da, 30 amino acids, unmodified short-profile GHRH analog
  • CJC-1295 with DAC: albumin-binding form with a longer presence
  • Shared: both require ≥98% HPLC and mass spec confirmation

FAQ

What is the difference between CJC-1295 with and without DAC?

DAC (drug affinity complex) is a chemical modification that makes the peptide bind serum albumin and persist longer in research assays. The no-DAC form is unmodified and has a shorter presence.

What purity should CJC-1295 no DAC be?

Accept ≥98% HPLC purity with mass spec confirming the expected molecular weight.

How is CJC-1295 no DAC stored?

Store lyophilized CJC-1295 no DAC at -20°C, protected from light and moisture. Reconstituted solution should be refrigerated.

Important: All products are sold strictly for laboratory and research purposes only — not for human or veterinary use. No medical or dosing guidance is provided.

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