What Makes a COA Trustworthy?
A genuine COA is batch-specific, lists HPLC purity and an MS molecular weight, and can be independently verified — anything less is a red flag. The document is the core of peptide quality control, and a fake or vague COA invalidates every result that depends on the material.
Check 1: Batch Matching
Confirm the batch number on the COA matches the batch number on the vial or package you actually received, because a COA for a different batch tells you nothing about your material.
Check 2: HPLC Purity
The COA should state an HPLC purity of at least 98% with a clear peak-area percentage. Learn to read these numbers correctly in our HPLC report guide.
Check 3: Mass Spectrometry
The COA should include an MS spectrum whose molecular weight matches the peptide’s expected value, since a sample can be 98% pure by HPLC and still be the wrong peptide. This is why MS confirmation is non-negotiable.
Check 4 and 5: Salt Form and Independent Verification
Verify the salt form and TFA-removal status are stated, and check whether the COA can be traced to an independent third-party test rather than only the supplier’s own word. For the full qualification framework, see our supplier vetting guide.
If a COA fails any of these checks, request a corrected document or switch suppliers. To ask us for a sample COA before ordering, message WhatsApp: +852 4419 8097.
Frequently Asked Questions
Q1: How do I know if a COA is fake?
Check that the batch number matches your vial, that HPLC purity is stated (≥98%), and that an MS spectrum matches the peptide’s molecular weight — a missing or mismatched MS is the clearest red flag.
Q2: Should a COA include mass spectrometry?
Yes — MS confirms molecular identity, and a COA with HPLC only cannot prove the material is the correct peptide.
Q3: Can I request a COA before ordering?
Yes, a legitimate supplier will share a sample or batch COA on request before you commit to a large order.
Important: All products are sold strictly for laboratory and research purposes only — not for human or veterinary use. No medical, therapeutic, or dosing guidance is provided or implied. Researchers are responsible for compliance with their institution and local regulations.